https://www.pierre-francois-roux.com/tags/quantitative-genetics/ Recent content in Quantitative genetics on Pierre-François Roux Hugo -- gohugo.io en-us © 2021 Pierre-François Roux Wed, 27 Apr 2016 00:00:00 +0000 https://www.pierre-francois-roux.com/project/integrating-linkage-analysis-with-whole-genome-sequencing-to-dissect-complex-phenotypes/ Wed, 27 Apr 2016 00:00:00 +0000 https://www.pierre-francois-roux.com/project/integrating-linkage-analysis-with-whole-genome-sequencing-to-dissect-complex-phenotypes/ The ultimate goal of quantitative trait loci (QTL) mapping is not only to locate genomic regions associated with a phenotype, but to identify the genes and mechanisms that shape complex traits. This remains difficult because QTL intervals often span megabases and contain many positional candidates. Without additional information, causal inference tends to favor already-known functional candidates, which narrows discovery and can miss unexpected regulators. During my PhD, I worked on the genetic architecture of adiposity and energy metabolism in chicken models.